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![DLD, Recombinant, Human, His-Tag (Dihydrolipoyl Dehydrogenase, Mitochondrial, DLDH, E3, GCSL, LAD, P](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
301198.100 | 100 µg | - | - |
3 - 19 business days* |
537.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DLD (Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), is... more
Product information "DLD, Recombinant, Human, His-Tag (Dihydrolipoyl Dehydrogenase, Mitochondrial, DLDH, E3, GCSL, LAD, P"
DLD (Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), is a component of the glycine cleavage system as well as of the alpha ketoacid dehydrogenase complexes. DLD is a flavin-dependent oxidoreductase and functions as a component of the alpha-keto acid dehydrogenase, the pyruvate dehydrogenase, the alpha-ketoglutarate dehydrogenase, the branched-chain alpha-keto acid dehydrogenase and as the L protein in the mitochondrial glycine cleavage system. Mutations in DLD protein can result in MSuD (maple syrup urine disease) and congenital infantile lactic acidosis. Recombinant human DLD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa36-509 and 511aa of human DLD, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~54.4kD, Specific Activity: >50units/ml, Unit Definition: One unit will reduce 1.0umole of DL-dihydrolipoamide per minute at pH 7.4 at 25ºC, AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMADQ PIDADVTVIG SGPGGYVAAI KAAQLGFKTV CIEKNETLGG TCLNVGCIPS KALLNNSHYY HMAHGKDFAS RGIEMSEVRL NLDKMMEQKS TAVKALTGGI AHLFKQNKVV HVNGYGKITG KNQVTATKAD GGTQVIDTKN ILIATGSEVT PFPGITIDED TIVSSTGALS LKKVPEKMVV IGAGVIGVEL GSVWQRLGAD VTAVEFLGHV GGVGIDMEIS KNFQRILQKQ GFKFKLNTKV TGATKKSDGK IDVSIEAASG GKAEVITCDV LLVCIGRRPF TKNLGLEELG IELDPRGRIP VNTRFQTKIP NIYAIGDVVA GPMLAHKAED EGIICVEGMA GGAVHIDYNC VPSVIYTHPE VAWVGKSEEQ LKEEGIEYKV GKFPFAANSR AKTNADTDGM VKILGQKSTD RVLGAHILGP GAGEMVNEAA LALEYGASCE DIARVCHAHP TLSEAFREAN LAASFGKSIN F, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | DLD, GCSL, Dihydrolipoamide dehydrogenase, Glycine cleavage system L protein, Dihydrolipoyl dehydrogenase, mitochondrial |
Supplier: | United States Biological |
Supplier-Nr: | 301198 |
Properties
Conjugate: | No |
MW: | 54,4 |
Format: | Highly Purified |
Database Information
KEGG ID : | K00382 | Matching products |
UniProt ID : | P09622 | Matching products |
Gene ID | GeneID 1738 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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