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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
506167.50 | 50 µg | - | - |
3 - 19 business days* |
454.00€
|
||
506167.250 | 250 µg | - | - |
3 - 19 business days* |
1,212.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CNTFR, also known as ciliary neurotrophic factor receptor subunit alpha preproprotein, is... more
Product information "CNTFR, Recombinant, Human, aa23-342, His-Tag (Ciliary Neurotrophic Factor Receptor Subunit alpha, CN"
CNTFR, also known as ciliary neurotrophic factor receptor subunit alpha preproprotein, is expressed in glial cells within the central and peripheral nervous systems. It stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types such as sensory, sympathetic, ciliary and motor neurons. This protein has a structure unrelated to the receptors utilized by the nerve growth factor family of neurotrophic molecules, but instead is most homologous to the receptor for a cytokine, interleukin-6. Also, it possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage. It activates downstream signaling molecules such as STAT-3 in areas of the hypothalamus which regulate food intake. Description: Recombinant protein corresponding to aa23-342 of human CNTFR, fused to His-tag at C-terminus, expressed in Baculovirus, Molecular Weight: ~36.9kD (329aa), ~40-57kD (SDS-PAGE under reducing conditions), Endotoxin: <1EU/1ug (LAL), AA Sequence: ADPQRHSPQE APHVQYERLG SDVTLPCGTA NWDAAVTWRV NGTDLAPDLL NGSQLVLHGL ELGHSGLYAC FHRDSWHLRH QVLLHVGLPP REPVLSCRSN TYPKGFYCSW HLPTPTYIPN TFNVTVLHGS KIMVCEKDPA LKNRCHIRYM HLFSTIKYKV SISVSNALGH NATAITFDEF TIVKPDPPEN VVARPVPSNP RRLEVTWQTP STWPDPESFP LKFFLRYRPL ILDQWQHVEL SDGTAHTITD AYAGKEYIIQ VAAKDNEIGT WSDWSVAAHA TPWTEEPRHL TTEAQAAETT TSTTSSLAPP PTTKICDPGE LGSHHHHHH, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | CNTFR, CNTFR-alpha, CNTF receptor subunit alpha, Ciliary neurotrophic factor receptor subunit alpha |
Supplier: | United States Biological |
Supplier-Nr: | 506167 |
Properties
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | human |
MW: | 36.93 kD |
Purity: | >95% (SDS-PAGE) |
Database Information
KEGG ID : | K05059 | Matching products |
UniProt ID : | P26992 | Matching products |
Gene ID | GeneID 1271 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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