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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSH030723.50 | 50 µg | - |
7 - 16 business days* |
1,025.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: A DNA sequence encoding the human CANT1 (Q8WVQ1-1) extracellular domain... more
Product information "CANT1 Protein (His tag) (recombinant human)"
Protein Construction: A DNA sequence encoding the human CANT1 (Q8WVQ1-1) extracellular domain (Gly 80-Ile 401) was fused with polyhistidine tag at the N-terminus. Sequence: Gly 80-Ile 401. Fusion tag: N-His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 40 kDa. Protein function: CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate. Two isoenzymes are found in commercial preparations from S. tuberosum. One with a higher ratio of substrate selectivity for ATP: ADP and another with no selectivity. It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP -> NDP + Pi -> NMP + 2Pi. The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes are implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate. CANT1 functions as a calcium-dependent nucleotidase with a preference for UDP. Defects in CANT1 are the cause of desbuquois dysplasia. Protein function: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP (PubMed:12234496, PubMed:15248776, PubMed:15006348, PubMed:16835225). Involved in proteoglycan synthesis (PubMed:22539336). [The UniProt Consortium]
Keywords: | CANT1, SHAPY, SCAN-1, Apyrase homolog, Putative MAPK-activating protein PM09, Soluble calcium-activated nucleotidase 1, Putative NF-kappa-B-activating protein 107, Recombinant Human CANT1 Protein (His tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSH030723 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | 38 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K12304 | Matching products |
UniProt ID : | Q8WVQ1 | Matching products |
Gene ID | GeneID 124583 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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