Androgen Receptor, Rat (AR), Purified

Control Peptide for A2281-02D (antiserum) and A2281-02G (affinity purified). Synthetic peptide consisting of 22aa near the N-terminus of Rat Androgen Receptor. This sequence demonstrates 100% homology with human AR. Species crossreactivity: Mouse, rat and human. , Androgen receptor (AR) belongs to the steroid hormone nuclear receptor superfamily. It functions as an androgen-dependent transcriptional factor that regulates genes for cell proliferation and differentiation. Upon binding to androgen, the androgen receptor (AR) can translocate into the nucleus and bind to androgen response element(s) to modulate its target genes. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution ELISA: 1:10,000-1:50,000 using 50-100ng control peptide/well., Optimal dilution to be determined by research, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.