ALKBH7 PrEST Antigen

ALKBH7 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST87339.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: May function as protein hydroxylase, can catalyze auto- hydroxylation at... more
Product information "ALKBH7 PrEST Antigen"
Protein function: May function as protein hydroxylase, can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ABH7, ALKBH7, EC=1.14.11.-, Spermatogenesis-associated protein 11, Alkylated DNA repair protein alkB homolog 7, Spermatogenesis cell proliferation-related protein, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7
Supplier: Atlas Antibodies
Supplier-Nr: APrEST87339

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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