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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-APrEST91059.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Dioxygenase that mediates demethylation of DNA and RNA containing... more
Product information "ALKBH3 PrEST Antigen"
Protein function: Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A) (PubMed:12486230, PubMed:12594517, PubMed:16174769, PubMed:26863196, PubMed:26863410). Repairs alkylated DNA containing 1-methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation (PubMed:12486230, PubMed:12594517, PubMed:16174769, PubMed:25944111). Has a strong preference for single- stranded DNA (PubMed:12486230, PubMed:12594517, PubMed:16174769). Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3 (PubMed:22055184). Also acts on RNA (PubMed:12594517, PubMed:16174769, PubMed:26863196, PubMed:26863410, PubMed:16858410). Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of messenger RNAs (mRNAs) highly enriched within 5'-untranslated regions (UTRs) and in the vicinity of start codons (PubMed:26863196, PubMed:26863410). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:22055184, PubMed:16858410). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: | hABH3, DEPC-1, Prostate cancer antigen 1, Alkylated DNA repair protein alkB homolog 3, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | APrEST91059 |
Properties
Application: | Control antigen |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
Database Information
KEGG ID : | K10860 | Matching products |
UniProt ID : | Q96Q83 | Matching products |
Gene ID | GeneID 221120 | Matching products |
Handling & Safety
Storage: | -20°C (avoid repeat freezing and thawing cycles) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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