MMP Inhibitor I (trifluoroacetate salt)

MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 µM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, alpha-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.Formal Name: (S)-1-((2-aminobenzoyl)glycyl)-N-((R)-1-(((R)-1-(hydroxyamino)-1-oxopropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide, trifluoroacetate salt. Synonyms: Abz-GP-DLeu-DAla-NH-OH, FN 439, Matrix Metalloproteinase Inhibitor I. Molecular Formula: C23H35N6O6 . XCF3COOH. Formula Weight: 491.6. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: CC(C)C[C@H](C(N[C@H](C)C(NO)=O)=O)NC([C@H]1N(C(CNC(C2=C(N)C=CC=C2)=O)=O)CCC1)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C23H34N6O6.C2HF3O2/c1-13(2)11-17(22(33)26-14(3)20(31)28-35)27-23(34)18-9-6-10-29(18)19(30)12-25-21(32)15-7-4-5-8-16(15)24,3-2(4,5)1(6)7/h4-5,7-8,13-14,17-18,35H,6,9-12,24H2,1-3H3,(H,25,32)(H,26,33)(H,27,34)(H,28,31),(H,6,7)/t14-,17-,18+,/m1./s1. InChi Key: GPSGGQYPYRTZQT-WQYGLUBDSA-N.