125 products were found matching "K01388"!

Protein function: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated...

MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a wide range of...

Batimastat is a broad spectrum inhibitor of matrix metalloproteinases (MMP), with IC50 values of 1-5 nM for all MMPs tested, including MMP-1, -2, -3, -7, -9, -13, and -14. It also potently inhibits TNFalpha-converting enzyme (IC50 = 14.9 nM). Because of its action on MMPs, batimastat has anti-proliferative,...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive...

The Fluorogenic MMP1 Assay Kit is designed to measure MMP1 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.

Isolated from Aspergillus niger. Matrix metalloproteinase-1 (MMP-1, Type I collagenase) inhibitor. HIV-1 integrase inhibitor.

Protein function: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. [The UniProt Consortium]

Human matrix metallopeptidase-1 (MMP1), also known as CLG, Interstitial Collagenase, Fibroblast Collagenase, and EC 3.4.24.7 (GenBank Accession No. NM_002421), a.a. 20-469 (end), with C-terminal His-tag, MW=53 kDa, expressed in an HEK293 cell expression system. Protein function: Cleaves collagens of types I, II, and...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a...

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive...