Bz-FVR-AMC (trifluoroacetate salt)

Bz-FVR-AMC is a fluorogenic peptide substrate for bovine cathepsins S and H, Xenopus endopeptidase XSCEP1, and esterase E-II from B. gabonica venom, among others. Upon enzymatic cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify enzyme activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name: N-((S)-1-(((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide, trifluoroacetate salt. Synonyms: Benzoyl-Phe-Val-Arg-AMC, Thrombin Fluorogenic Substrate III. Molecular Formula: C37H43N7O6 . XCF3COOH. Formula Weight: 681.8. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NC2=CC=C(C(C)=CC(O3)=O)C3=C2)=O)=O)=O)C4=CC=CC=C4.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C37H43N7O6.C2HF3O2/c1-22(2)32(44-35(48)29(20-24-11-6-4-7-12-24)43-33(46)25-13-8-5-9-14-25)36(49)42-28(15-10-18-40-37(38)39)34(47)41-26-16-17-27-23(3)19-31(45)50-30(27)21-26,3-2(4,5)1(6)7/h4-9,11-14,16-17,19,21-22,28-29,32H,10,15,18,20H2,1-3H3,(H,41,47)(H,42,49)(H,43,46)(H,44,48)(H4,38,39,40),(H,6,7)/t28-,29-,32-,/m0./s1. InChi Key: ADUYTEHLGOONRQ-AVTZECDJSA-N.