89 products were found matching "K01368"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CTSS antibody detects Cathepsin S, a lysosomal cysteine protease that degrades extracellular matrix and participates in antigen processing. The UniProt recommended name is Cathepsin S (CTSS). This proteolytic enzyme plays a central role in...

LY3000328 is a potent cathepsin S inhibitor (IC50 = 7.7 nM for the human enzyme). It is selective for cathepsin S over cathepsin L, K, B, and V (IC50s = >10,000, >10,000, 4,390, and 21,500 nM, respectively). LY3000328 (1-30 mg/kg) reduces aortic diameter in a mouse model of calcium chloride-induced abdominal aortic...

E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...

K777 is a cysteine protease inhibitor. It inhibits human cathepsin S (Ki = 0.002 µM) and human cathepsin L (Ki = 0.05 µM), which cleaves the severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein, also known as the surface glycoprotein. K777 is selective for these proteases over human cathepsin K,...

Protein function: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. [The UniProt Consortium]

Active human cathepsin S (GenBank Accession No. NM_004079.3), CD33 signal peptide(1-16aa) cathepsin S (a-a 17-331), with C-terminal HIS tag, W=37 kDa, expressed in FreeStyle 293-F cells.

Natural and recombinant human Cathepsin S. There is no detectable cross-reactivity with other relevant proteins. Protein function: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the...

E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.

Bz-FVR-AMC is a fluorogenic peptide substrate for bovine cathepsins S and H, Xenopus endopeptidase XSCEP1, and esterase E-II from B. gabonica venom, among others. Upon enzymatic cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify enzyme activity. AMC displays...

Protein function: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L. [The UniProt Consortium]