Ac-LEHD-AMC

Ac-LEHD-AMC
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-13426 5 mg -

3 - 8 business days*

171.00€
 
Caspase 9 is a member of the CED-3 subfamily of the caspase family of cysteine proteases that... more
Product information "Ac-LEHD-AMC"
Caspase 9 is a member of the CED-3 subfamily of the caspase family of cysteine proteases that play an essential role in the execution phase of apoptosis. These enzymes share a dominant primary specificity for cleaving bonds following aspartic acid residues. Initiator caspases (such as caspase 8) activate effector caspases, such as caspases 3 and 7. The effector caspases then cleave cellular substrates ultimately leading to the morphological changes of apoptosis. Ac-LHED-AMC is a selective fluorogenic substrate for caspase 9. The caspase 9-induced hydrolysis of Ac-LHED-AMC results in the release of AMC fluorophore that is detected using an excitation wavelength of approx. 365 nm and an emission wavelengh of approx. 450 nm. The assay can be run in the assay buffer consisting of 50 mM MES, pH 6.5, 10% PEG 8000, 0.1% CHAPS, 5 mM DTT, and 1 mM EDTA.
Supplier: AAT Bioquest
Supplier-Nr: 13426

Properties

Application: Caspase-9 substrate
Conjugate: No

Database Information

CAS : 292633-16-0| Find alternatives
KEGG ID : K04399 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
Caution
Our products are for laboratory research use only: Not for administration to humans!
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