170 products were found matching "K04399"!

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase 9 is a key initiator caspase in the intrinsic (mitochondrial) apoptotic pathway, responsible for activating downstream effector caspases and orchestrating programmed cell death. In zebrafish (Danio rerio), Caspase 9 plays a conserved role in regulating...

Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Formal Name:...

Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used. This particular kit is designed to monitor cell apoptosis by measuring caspase 9 activity. Caspase 9 is a member of the CED-3 subfamily. Activated Caspase-9 cleaves downstream...

This kits makes use of a cell-permeant green fluorecent probe (FAM-LEHD-FMK ) that binds to active caspase-9 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage- induced apoptosis in a...

Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used. This particular kit is designed to monitor cell apoptosis by measuring caspase 9 activity. Caspase 9 is a member of the CED-3 subfamily. Activated Caspase-9 cleaves downstream...

This kits makes use of a cell-permeant green fluorecent probe (FAM-LEHD-FMK ) that binds to active caspase-9 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

This kits makes use of a cell-permeant red fluorecent probe (SR-LEHD-FMK ) that binds to active caspase-9 in living cells undergoing apoptosis. Excitation wavelength 560nm, emission 590nm.

Caspase 9 is a member of the CED-3 subfamily of the caspase family of cysteine proteases that play an essential role in the execution phase of apoptosis. These enzymes share a dominant primary specificity for cleaving bonds following aspartic acid residues. Initiator caspases (such as caspase 8) activate effector...

Caspase 9 is a member of the CED-3 subfamily of the caspase family of cysteine proteases that play an essential role in the execution phase of apoptosis. These enzymes share a dominant primary specificity for cleaving bonds following aspartic acid residues. Initiator caspases (such as caspase 8) activate effector...

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9. Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name:...