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Description: Z-LLNle-CHO is a cell permeable inhibitor of gamma-secretase. Z-LLNle-CHO induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response. Smiles: [C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(C)C)=O)(C(N[C@@H](CCCC)C=O)=O)CC(C)C. References: Ikezawa Y, Sakakibara-Konishi J, Mizugaki H, Oizumi S, Nishimura M. Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer. Int J Clin Oncol. 2017 Feb,22(1):59-69. doi: 10.1007/s10147-016-1031-8. Epub 2016 Aug 23. PubMed PMID: 27553958.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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