TAMRA-Amyloid-beta (1-40) Peptide (human) (trifluoroacetate salt)

TAMRA-Amyloid-beta (1-40) peptide is a fluorescently labeled peptide. Amyloid-beta (1-40) (Abeta40) peptide (Cay-21617) is a 40-residue protein fragment of Abeta42 (Cay-20574), a neurotoxic peptide found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease. Abeta40 is more abundant, less neurotoxic, and does not form oligomers as easily as Abeta42. TAMRA-Amyloid-beta (1-40) peptide is a labeled form of Abeta40 containing carboxytetramethyl rhodamine (TAMRA), which displays excitation/emission maxima of 543/572 nm, respectively.Formal Name: 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-xanthylium-L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valine, trifluoroacetate salt. Synonyms: TAMRA-Abeta (1-40), TAMRA-Abeta40. Molecular Formula: C219H315N55O62S . XCF3COOH. Formula Weight: 4742.3. Purity: >95%. Emission: 572 nm. Excitation: 543 nm. Formulation: (Request formulation change), A solid. Solubility: Formic Acid: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.O=C(N([H])[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(NCC(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(NCC(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)CCSC)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)C)=O)CC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)CC4=CN=CN4)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)CC(O)=O)=O)CC6=CN=CN6)=O)=O)CC7=CC=CC=C7)=O)=O)C)=O)CC(O)=O)C8=CC(C([O-])=O)=C(C9=C(C=C/%10)C(OC%11=C9C=CC(N(C)C)=C%11)=CC%10=[N+](C)/C)C=C8. InChi Code: InChI=1S/C219H315N55O62S.C2HF3O2/c1-29-115(19)181(212(327)235-100-165(283)242-143(77-107(3)4)198(313)252-142(72-76-337-28)195(310)266-175(109(7)8)210(325)233-96-162(280)230-97-167(285)265-177(111(11)12)215(330)270-180(114(17)18)218(334)335)272-216(331)182(116(20)30-2)271-185(300)117(21)239-163(281)98-231-187(302)135(51-40-42-73-220)247-205(320)152(89-161(223)279)259-209(324)157(103-276)244-166(284)101-234-211(326)176(110(9)10)267-208(323)155(92-173(296)297)260-193(308)140(66-70-169(288)289)246-183(298)118(22)240-196(311)146(79-120-45-34-31-35-46-120)256-201(316)148(81-122-49-38-33-39-50-122)262-213(328)179(113(15)16)269-207(322)144(78-108(5)6)254-189(304)136(52-41-43-74-221)248-191(306)138(64-68-160(222)278)250-202(317)149(84-125-93-226-104-236-125)258-204(319)151(86-127-95-228-106-238-127)263-214(329)178(112(13)14)268-194(309)141(67-71-170(290)291)251-199(314)145(82-123-54-59-130(277)60-55-123)243-164(282)99-232-188(303)156(102-275)264-206(321)154(91-172(294)295)261-203(318)150(85-126-94-227-105-237-126)257-190(305)137(53-44-75-229-219(224)225)249-200(315)147(80-121-47-36-32-37-48-121)255-192(307)139(65-69-168(286)287)245-184(299)119(23)241-197(312)153(90-171(292)293)253-186(301)124-56-61-131(134(83-124)217(332)333)174-132-62-57-128(273(24)25)87-158(132)336-159-88-129(274(26)27)58-63-133(159)174,3-2(4,5)1(6)7/h31-39,45-50,54-63,83,87-88,93-95,104-119,135-157,175-182,275-276H,29-30,40-44,51-53,64-82,84-86,89-92,96-103,220-221H2,1-28H3,(H59-,222,223,224,225,226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247,248,249,250,251,252,253,254,255,256,257,258,259,260,261,262,263,264,265,266,267,268,269,270,271,272,277,278,279,280,281,282,283,284,285,286,287,288,289,290,291,292,293,294,295,296,297,298,299,300,301,302,303,304,305,306,307,308,309,310,311,312,313,314,315,316,317,318,319,320,321,322,323,324,325,326,327,328,329,330,331,332,333,334,335),(H,6,7)/t115-,116-,117-,118-,119-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,. InChi Key: NFCHJCNIGDRYTD-PPHARLNUSA-N.