Boc-FLFLF

Boc-FLFLF is a formyl peptide receptor (FPR) antagonist (Ki = 1.46 µM). It inhibits increases in intracellular calcium levels, superoxide formation, and beta-glucuronidase release induced by the FPR agonist N-formyl-Met-Leu-Phe (fMLP, Cay-21495) in differentiated HL-60 cells (Kis = 0.43, 1.04, and 1.82 µM, respectively).Formal Name: N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L-phenylalanine. CAS Number: 73572-58-4. Synonyms: Boc-Phe-Leu-Phe-Leu-Phe, Boc-PLPLP, L-BOC-2. Molecular Formula: C44H59N5O8. Formula Weight: 786.0. Purity: >95%. Formulation: (Request formulation change), A solid. Peptide Sequence: Boc-FLFLF-OH. Solubility: Chloroform: Slightly soluble: 0.1-1 mg/ml, Methanol: Slightly soluble: 0.1-1 mg/ml. SMILES: O=C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)[C@@H](NC([C@H](CC(C)C)NC([C@@H](NC(OC(C)(C)C)=O)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3. InChi Code: InChI=1S/C44H59N5O8/c1-28(2)23-33(46-41(53)36(26-31-19-13-9-14-20-31)49-43(56)57-44(5,6)7)38(50)47-35(25-30-17-11-8-12-18-30)40(52)45-34(24-29(3)4)39(51)48-37(42(54)55)27-32-21-15-10-16-22-32/h8-22,28-29,33-37H,23-27H2,1-7H3,(H,45,52)(H,46,53)(H,47,50)(H,48,51)(H,49,56)(H,54,55)/t33-,34-,35-,36-,37-/m0/s1. InChi Key: NGNZQSPFQJCBJQ-LTLCPEALSA-N.