54 products were found matching "K04172"!

The formyl peptide receptors (FPR) are a class of G protein-coupled receptors involved in chemotaxis. FPR1 is a Gi-coupled GPCR. FPR1 is expressed in the vasculature, secretory epithelial cells, neurons and other tissues. FPR is involved in host defense against bacterial infection and in the clearance of damaged cells.

Cyclosporin H is a formyl peptide receptor antagonist.

N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPRs, Ki = 0.8 pM), which are mainly localized on polymorphonuclear and mononuclear phagocytes. Activation of FPRs by fMLF leads to cellular activation, which is characterized by cellular polarization, chemotaxis,...

Cyclosporin H is a natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 µM. Unlike cyclosporin A (Cay-12088), cyclosporin H does not bind cyclophilin to evoke an immunosuppressant response. Cyclosporin H has been reported to inhibit phorbol...

White solid. Soluble in 100% ethanol, acetone or ethyl acetate, insoluble in water. Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo, Antifungal, Potent and effective inhibitor of formyl peptide receptor (FPR) and formyl peptide-induced superoxide formation, Shows no...

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: FPR1. Antigen Species: Human

TC-FPR 43 is an agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). TC-FPR 43 induces calcium flux in CHO cells expressing human FPR2, Galpha15, and aequorin (EC50 = 0.044 µM) and in CHO-K1 cells expressing either human FPR1, human FPR2, mouse...

WKYMVm is a synthetic peptide agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). It induces calcium mobilization in ETFR rat basophilic leukemia cells transfected with FPR1 or FPR2 when used at a concentration of 0.1 nM. WKYMVm stimulates...

Protein function: High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...

Protein function: High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FPR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FPR1. Next,...

N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys (fNLFNYK) is a synthetic chemotactic peptide. It binds to the formyl peptide receptor (FPR, Kd = 2.2 nM). fNLFNYK has been conjugated to various fluorophores to monitor FPR internalization.Formal Name: N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine,...