Recombinant Human Sonic Hedgehog/SHH Protein (C24II)(Active) (RPES4749)

Sonic Hedgehog/SHH Recombinant Protein (C24II) (RPES4749) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum. [The UniProt Consortium]