GITR Ligand/TNFSF18 Protein (recombinant mouse)

GITR Ligand/TNFSF18 Protein (recombinant mouse)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB1868.10 10 µg - - -

9 - 20 business days*

145.00€
 
Endotoxin level: < 0.1 EU/µg. Protein function: Cytokine that binds to TNFRSF18/AITR/GITR... more
Product information "GITR Ligand/TNFSF18 Protein (recombinant mouse)"
Endotoxin level: < 0.1 EU/µg. Protein function: Cytokine that binds to TNFRSF18/AITR/GITR (PubMed:14521928, PubMed:14647196). Regulates T-cell responses (PubMed:14647196). Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation (PubMed:14608036, PubMed:15128759). Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B (PubMed:14521928, PubMed:14647196, PubMed:18178614). Triggers increased phosphorylation of STAT1 and up- regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (PubMed:24107315). [The UniProt Consortium]
Keywords: GITRL, Gitrl, Tnfsf18, GITR ligand, Glucocorticoid-induced TNF-related ligand, Tumor necrosis factor ligand superfamily member 18
Supplier: Assay Genie
Supplier-Nr: RPCB1868

Properties

Conjugate: No
Host: Human cells
Species reactivity: mouse
Purity: >95% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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