42 products were found matching "K05479"!

Human glucocorticoid-induced TNF-related ligand (GITRL), also known as AITRL, CD357L, or tumor necrosis factor ligand superfamily member 18 (TNFSF18). GenBank Accession No. NM_005092, a.a. 72-199 with an N-terminal His-tag, expressed in a HEK293 cell expression system. MW = 17.1 kDa. Note: this protein runs at a...

Recognizes human GITRL. Detects a band of about 15-17kDa by Western blot. Does not cross-react with mouse GITRL. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts...

The extracellular domain of mouse GITRL (amino acids 45-173) is fused at the N-terminus to a FLAG(R)-tag. Induces GITR-mediated NF-kappaB activation in HEK 293 cells. Liquid. 0.2µm-filtered solution in 10mM glycine, pH 10.0. GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC),...

Recombinant CHO-K1 cell constitutively expressing full length human GITRL (NP_005083.2). Surface expression is confirmed by flow cytometry.

Anti-GITRL Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with GITRL from other sources has not been determined. Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T- cell responses. Can function as costimulator and lower the...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is...

Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. (www.uniprot.org) Produced in E.coli, containing 125 amino acid residues of the human AITRL (homologous to the extracellular domain...

Human recombinant AITRL produced in E.coli is a single, non-glycosylated polypeptide chain containing 129 amino acids (72-199) and having a molecular mass of 14.6 kDa. Osteostat is the cytokine that binds to TNFRSF18/AITR/GITR and is important for interactions between activated T-lymphocytes and endothelial cells...

Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T- cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers...

Protein function: Cytokine that binds to TNFRSF18/AITR/GITR (PubMed:14521928, PubMed:14647196). Regulates T-cell responses (PubMed:14647196). Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation (PubMed:14608036, PubMed:15128759). Important for interactions between...

The GITR:GITRL TR-FRET Assay is designed to measure the inhibition of GITR binding to GITRL in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and...

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is...