EZ Cap(TM) Firefly Luciferase mRNA (mo5U)

EZ Cap(TM) Firefly Luciferase mRNA encodes for luciferase, a protein originally isolated from the firefly P. pyralis, that catalyzes the ATP-dependent oxidation of the molecule luciferin resulting in chemiluminescence at a wavelength of approximately 560 nm. It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap 1 structure with high capping efficiency. EZ Cap(TM) Firefly Luciferase mRNA is also polyadenylated and modified with 5-methyoxy-UTP (mo5U) to reduce host cell immune response and enhance mRNA stability. Encapsulation of EZ Cap(TM) Firefly Luciferase mRNA (mo5U) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of luciferase protein in vitro or in vivo.Synonyms: EZ Cap(TM) Firefly Luciferase mRNA (5-moUTP). Emission: ~560 nm. Formulation: (Request formulation change), 1 mM Sodium citrate, pH 6.4.