N-Phenylacetyl-L-Prolylglycine ethyl ester

N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity, indicating a potential application in the treatment of neurodegenerative diseases. It also demonstrates antioxidant and anti-inflammatory effects, which have been examined in the context of an anti-diabetic agent. This compound was recently identified in illegal designer herbal products distributed in Japan and is intended for research and forensic purposes only.Formal Name: 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester. CAS Number: 157115-85-0. Molecular Formula: C17H22N2O4. Formula Weight: 318.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O=C(CC1=CC=CC=C1)N2[C@H](C(NCC(OCC)=O)=O)CCC2. InChi Code: InChI=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1. InChi Key: PJNSMUBMSNAEEN-AWEZNQCLSA-N.