4-Nonylphenol-2,3,5,6-d4

4-Nonylphenol-2,3,5,6-d4 is intended for use as an internal standard for the quantification of 4-nonylphenol by GC- or LC-MS. 4-Nonylphenol is a degradation product of the nonionic surfactant nonylphenol ethoxylate and an endocrine disruptor. It induces estrogen receptor alpha (ERalpha) reporter gene expression in MCF-7 cells expressing the human receptor when used at a concentration of 100 nM. 4-Nonylphenol (20 µM) decreases triglyceride accumulation and reduces expression of the adipogenesis marker genes Ppargamma1, Ppargamma2, Cebpa, Cebpbeta, and Fabp4 in differentiated 3T3-L1 adipocytes but promotes triglyceride accumulation and adipogenesis in C3H/10T1/2 mesenchymal stem cells (MSCs). It has been found as a contaminant in food and rivers.Formal Name: 4-nonyl-phen-2,3,4,5-d4-ol. CAS Number: 1173019-62-9. Synonyms: 4-NP-2,3,5,6-d4, NPH-2,3,5,6-d4. Molecular Formula: C15H20D4O. Formula Weight: 224.4. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A low melting solid. Solubility: Chloroform: Slightly soluble, Methanol: Slightly soluble. SMILES: CCCCCCCCCC1=C([2H])C([2H])=C(C([2H])=C1[2H])O. InChi Code: InChI=1S/C15H24O/c1-2-3-4-5-6-7-8-9-14-10-12-15(16)13-11-14/h10-13,16H,2-9H2,1H3/i10D,11D,12D,13D. InChi Key: IGFHQQFPSIBGKE-ZGAVCIBUSA-N.