Tauroursodeoxycholic Acid (sodium salt hydrate)

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's disease, ischemic brain injury, and retinal disorders.Formal Name: 2-[[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt, hydrate. Synonyms: 3alpha,7beta-dihydroxy-5beta-cholanoyl Taurine, Sodium Tauroursodeoxycholate, TUDCA, UR-906. Molecular Formula: C26H44NO6S . Na [XH2O]. Formula Weight: 521.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 20 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: C[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+].O. InChi Code: InChI=1S/C26H45NO6S.Na.H2O/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29,,/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33),,1H2/q,+1,/p-1/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-,,/m1../s1. InChi Key: KSCHEDMXAHFUNB-GUBAPICVSA-M.