PtdIns-(4,5)-P2-fluorescein (triethylammonium salt)

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2-fluorescein is a fluorescent probe for any protein with a high-affinity binding interaction with inositol-(4,5)-triphosphate phospholipids, such as PI3K, PTEN, or PH-domain-containing proteins.Formal Name: 1-(1-octadecanoyl-fluorescein-2R-octadecanoylphosphatidyl)inositol-4,5-bisphosphate, pentatriethylammonium salt. Synonyms: DOPI-4,5-P2-fluorescein, Phosphatidylinositol-4,5-diphosphate C-8-fluorescein, PI(4,5)P2-fluorescein, PIP2[4',5']-fluorescein. Molecular Formula: C46H55NO25P3 . 5C6H16N. Formula Weight: 1625.8. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: O=C1C=CC2=C(C3=C(C(O)=O)C=C(C(NCCCCCCCC(OC[C@@H](OC(CCCCCCC)=O)COP([O-])(O[C@@H]4[C@H](O)[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]4O)=O)=O)=O)C=C3)C(C=CC(O)=C5)=C5OC2=C1.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CCO=C1C=CC2=C(C3=C(C(O)=O)C=C(C(NCCCCCCCC(OC[C@@H](OC(CCCCCCC)=O)COP([O-])(O[C@@H]4[C@H](O)[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]4O)=O)=O)=O)C=C3)C(C=CC(O)=C5)=C5OC2=C1.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC. InChi Code: InChI=1S/C46H60NO25P3.7C6H15N/c1-2-3-4-6-10-13-37(51)68-29(25-67-75(64,65)72-42-39(52)40(53)43(70-73(58,59)60)44(41(42)54)71-74(61,62)63)24-66-36(50)12-9-7-5-8-11-20-47-45(55)26-14-17-30(33(21-26)46(56)57)38-31-18-15-27(48)22-34(31)69-35-23-28(49)16-19-32(35)38,7*1-4-7(5-2)6-3/h14-19,21-23,29,39-44,48,52-54H,2-13,20,24-25H2,1H3,(H,47,55)(H,56,57)(H,64,65)(H2,58,59,60)(H2,61,62,63),7*4-6H2,1-3H3/p+2/t29-,39-,40+,41+,42-,43-,44-,,,,,,,/m1......./s1. InChi Key: GXMZRZPMWPMFQI-RTACQUFLSA-P.