PtdIns-(3,4)-P2 (1,2-dipalmitoyl) (sodium salt)

The phosphatidylinositols (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns is phosphorylated to mono- (PtdIns-P, PIP), di- (PtdIns-P2, PIP2) and triphosphates (PtdIns-P3, PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.Formal Name: 1-(1,2R-dihexadecanoylphosphatidyl)inositol-3,4-bisphosphate, trisodium salt. Synonyms: DPPI-3,4-P2, Phosphatidylinositol-3,4-diphosphate C-16, PI(3,4)P2 (16:0/16:0), PIP2[3',4'](16:0/16:0). Molecular Formula: C41H78O19P3 . 3Na. Formula Weight: 1036.9. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. Solubility: 50 mM HEPES*: 5 mg/ml, CHCl3:CH3OH:H2O (3:2:1): 10 mg/ml, PBS (pH 7.2): 1 mg/ml (opaque solution). SMILES: CCCCCCCCCCCCCCCC(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](O)[C@H]1O)([O-])=O)OC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C41H81O19P3.3Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-39-36(44)37(45)40(58-61(47,48)49)41(38(39)46)59-62(50,51)52,,,/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54. InChi Key: STJBVCQNLFXTFJ-AAOIFZENSA-K. Side Chain Carbon Sum: 32:0.