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Product information "PtdIns-(3,4,5)-P3-fluorescein (triethylammonium salt)"
The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates an intricate signaling cascade that has been implicated in cancer. PtdIns-(3,4,5)-P3 fluorescein is a fluorescent probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.Formal Name: 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt. Synonyms: DOPI-3,4,5-P3-fluorescein, Phosphatidylinositol-3,4,5-triphosphate C-8-fluorescein, PI(3,4,5)P3-fluorescein, PIP3[3',4',5']-fluorescein. Molecular Formula: C46H54NO28P4 . 7C6H16N. Formula Weight: 1908.2. Purity: >90%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: O=C1C=CC2=C(C3=C(C(O)=O)C=C(C(NCCCCCCCC(OC[C@@H](OC(CCCCCCC)=O)COP([O-])(O[C@@H]4[C@H](O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]4O)=O)=O)=O)C=C3)C(C=CC(O)=C5)=C5OC2=C1.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC. InChi Code: InChI=1S/C46H61NO28P4.7C6H15N/c1-2-3-4-6-10-13-37(51)70-29(25-69-79(66,67)75-41-39(52)42(72-76(57,58)59)44(74-78(63,64)65)43(40(41)53)73-77(60,61)62)24-68-36(50)12-9-7-5-8-11-20-47-45(54)26-14-17-30(33(21-26)46(55)56)38-31-18-15-27(48)22-34(31)71-35-23-28(49)16-19-32(35)38,7*1-4-7(5-2)6-3/h14-19,21-23,29,39-44,48,52-53H,2-13,20,24-25H2,1H3,(H,47,54)(H,55,56)(H,66,67)(H2,57,58,59)(H2,60,61,62)(H2,63,64,65),7*4-6H2,1-3H3/t29-,39+,40+,41-,42+,43-,44-,,,,,,,/m1......./s1. InChi Key: CZNXJRILJYPMCT-LKBISYOHSA-N.
Keywords:
1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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