PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt)

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) is intended for use as an internal standard for the quantification of PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) (Cay-64920) by GC- or LC-MS.. The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin alpha and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see references and .Formal Name: 1-(1,2R-dihexadecanoyl (2,2',3,3',4,4',5,5',6,6',7,7',8,8',9,9',10,10',11,11',12,12',13,13',14,14',15,16,16,16-d62)phosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt. Synonyms: DPPI-3,4,5-P3-d62, Phosphatidylinositol-3,4,5-trisphosphate C-16-d62, PI(3,4,5)P3 (16:0/16:0)-d62, PIP3[3',4',5'](16:0/16:0)-d62. Molecular Formula: C41H16D62O22P4 . 4Na. Formula Weight: 1201.3. Purity: >99% deuterated forms (d1-d62). Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 10 mg/ml. SMILES: O[C@@H]1[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@@H](O)[C@H]1OP([O-])(OCC(COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H. InChi Code: InChI=1S/C41H82O22P4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)57-31-33(59-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-58-67(55,56)63-38-36(44)39(60-64(46,47)48)41(62-66(52,53)54)40(37(38)45)61-65(49,50)51/h33,36-41,44-45H,3-32H2,1-2H3,(H,. InChi Key: ZSZXYWFCIKKZBT-ZJSKRBLYSA-J. Side Chain Carbon Sum: 32:0.