Prostaglandin E2 methyl ester

Prostaglandin E2 methyl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14011-500 500 µg -

3 - 10 business days*

32.00€
Cay14011-1 1 mg -

3 - 10 business days*

60.00€
Cay14011-5 5 mg -

3 - 10 business days*

250.00€
Cay14011-10 10 mg -

3 - 10 business days*

438.00€
 
Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 (Cay-14010) with enhanced... more
Product information "Prostaglandin E2 methyl ester"
Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 (Cay-14010) with enhanced lipid solubility. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) values of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue. Formal Name: 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, methyl ester. CAS Number: 31753-17-0. Synonyms: Dinoprostone methyl ester, PGE2 methyl ester. Molecular Formula: C21H34O5. Formula Weight: 366.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: >25 mg/ml, DMSO: >30 mg/ml, Ethanol: >50 mg/ml, PBS pH 7.2: >150 µg/ml. SMILES: O=C1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C21H34O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-18,20,22,24H,3-4,6-7,9-12,15H2,1-2H3/b8-5-,14-13+/t16-,17+,18+,20+/m0/s1. InChi Key: WGCXTGBZBFBQPP-ZYONDNFOSA-N.
Keywords: Dinoprostone methyl ester, PGE2 methyl ester, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 14011

Properties

Application: Bioactive lipid assays
MW: 366.5 D
Formula: C21H34O5
Purity: >98%
Format: Solution

Database Information

CAS : 31753-17-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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