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Prostaglandin E2 (PGE2) is the major eicosanoid product of cyclooxygenase-1 and 2 in epithelial cells, leukocytes, reproductive tissues, and many others. PGE2 contracts smooth muscle, protects the gastric mucosa, modulates immune function, and regulates fertility and implantation. PGE2 acts through at least four 7-transmembrane G protein-coupled receptors, EP1-EP4. PGE2-biotin is an affinity probe which allows PGE2 to be detected through an interaction with the biotin ligand. PGE2-biotin was designed to allow PGE2 to be detected in complexes with transmembrane receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of PGs.Formal Name: 11alpha,15S-dihydroxy-9-oxo-prosta-5Z,13E-dien-1-oyl-N'-biotinoyl-1,5-diaminopentane. CAS Number: 2641624-60-2. Synonyms: PGE2-biotin. Molecular Formula: C35H58N4O6S. Formula Weight: 662.9. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): .1 mg/ml. SMILES: [H][C@]12[C@](N([H])C(N2[H])=O)([H])CS[C@@H]1CCCCC(NCCCCCN([H])C(CCC/C=C\C[C@H]3C(C[C@@H](O)[C@@H]3/C=C/[C@@H](O)CCCCC)=O)=O)=O. InChi Code: InChI=1S/C35H58N4O6S/c1-2-3-7-14-25(40)19-20-27-26(29(41)23-30(27)42)15-8-4-5-9-17-32(43)36-21-12-6-13-22-37-33(44)18-11-10-16-31-34-28(24-46-31)38-35(45)39-34/h4,8,19-20,25-28,30-31,34,40,42H,2-3,5-7,9-18,21-24H2,1H3,(H,36,43)(H,37,44)(H2,38,39,45)/. InChi Key: PREZBUUQJJPPFV-VTPUZKRBSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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