Oleyl Anilide

Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT, IC50 = 26 µM). It induces splenomegaly in C57BL/6 mice and leads to weakness, weight loss, cachexia, and death in A/J mice with increases in serum IgG and IgM levels in both strains. Oleyl anilide has been found in aniline-denatured rapeseed cooking oil, which has been associated with toxic oil syndrome, a chemically induced autoimmune syndrome characterized by acute pulmonary inflammation and eosinophilia, severe myalgia, and chronic peripheral neuropathy.Formal Name: N-phenyl-9Z-octadecenamide. CAS Number: 5429-85-6. Synonyms: OA, Oleic Acid Anilide, Oleylanilide. Molecular Formula: C24H39NO. Formula Weight: 357.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 243 nm. SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)Nc1ccccc1. InChi Code: InChI=1S/C24H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-24(26)25-23-20-17-16-18-21-23/h9-10,16-18,20-21H,2-8,11-15,19,22H2,1H3,(H,25,26)/b10-9-. InChi Key: YPUOCYKJOLQYQS-KTKRTIGZSA-N.