OC2-K3-E10

OC2-K3-E10 is an ionizable cationic lipid (pKa = 6.8). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in transgenic mice.Formal Name: 3,3'-((2-hydroxyethyl)azanediyl)bis(N-(3-(bis(2-hydroxydecyl)amino)propyl)propanamide). CAS Number: 2933216-12-5. Synonyms: I-28. Molecular Formula: C54H111N5O7. Formula Weight: 942.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 10 mg/ml. SMILES: OCCN(CCC(NCCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)=O)CCC(NCCCN(CC(O)CCCCCCCC)CC(CCCCCCCC)O)=O. InChi Code: InChI=1S/C54H111N5O7/c1-5-9-13-17-21-25-31-49(61)45-58(46-50(62)32-26-22-18-14-10-6-2)39-29-37-55-53(65)35-41-57(43-44-60)42-36-54(66)56-38-30-40-59(47-51(63)33-27-23-19-15-11-7-3)48-52(64)34-28-24-20-16-12-8-4/h49-52,60-64H,5-48H2,1-4H3,(H,55,65)(H,56,66). InChi Key: QUXHZASDVBKOSF-UHFFFAOYSA-N.