Lipid C-1

Lipid C-1 is an ionizable cationic amino lipid and a derivative of SM-102 (Cay-33474). It has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro. LNPs containing lipid C-1 and encapsulating an mRNA reporter induce higher luciferase expression in Calu-3 cells than SM-102.Formal Name: 8-[(3-hydroxypropyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester. CAS Number: 2244715-87-3. Synonyms: Lipid 142. Molecular Formula: C45H89NO5. Formula Weight: 724.2. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Chloroform: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: OCCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCC(OCCCCCCCCCCC)=O. InChi Code: InChI=1S/C45H89NO5/c1-4-7-10-13-16-17-18-24-32-42-50-44(48)36-29-25-31-39-46(40-33-41-47)38-30-23-19-22-28-37-45(49)51-43(34-26-20-14-11-8-5-2)35-27-21-15-12-9-6-3/h43,47H,4-42H2,1-3H3. InChi Key: QADMLAYSFUXEEL-UHFFFAOYSA-N.