Linoleoyl Glycine

Linoleoyl Glycine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay9000326-5 5 mg -

6 - 10 business days*

Cay9000326-10 10 mg -

6 - 10 business days*

Cay9000326-50 50 mg -

6 - 10 business days*

Arachidonyl glycine, the conjugate of arachidonic acid and glycine produced in mammalian brain,... more
Product information "Linoleoyl Glycine"
Arachidonyl glycine, the conjugate of arachidonic acid and glycine produced in mammalian brain, skin, and spinal cord, is a structural analog of anandamide (AEA) that is reported to have analgesic activities in whole animal experiments. It has poor affinity for the central cannabinoid (CB1) receptor, high-affinity for the G protein-coupled receptor GPR-18, and is metabolically regulated by fatty acid amide hydrolase (FAAH) activity. LinGly is an endogenous homolog of linoleoyl ethanolamide, an arachidonyl glycine. It inhibits the hydrolysis of AEA in FAAH-containing N18TG2 cell membranes with an IC50 value of ~25 µM, which is less potent than that of arachidonyl glycine (IC50 = 7 µM). The biological significance of LinGly has not yet been determined. Formal Name: N-9Z,12Z-1-oxo-octadecadien-1-yl-glycine. CAS Number: 2764-03-6. Synonyms: Glycine Linoleamide, LinGly, N-Linoleoyl Glycine. Molecular Formula: C20H35NO3. Formula Weight: 337.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 15 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 2 mg/ml. SMILES: CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O. InChi Code: InChI=1S/C20H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)21-18-20(23)24/h6-7,9-10H,2-5,8,11-18H2,1H3,(H,21,22)(H,23,24)/b7-6-,10-9-. InChi Key: YCRHZEHWEYAHCO-HZJYTTRNSA-N.
Keywords: Glycine Linoleamide, LinGly, N-Linoleoyl Glycine, N-9Z,12Z-1-oxo-octadecadien-1-yl-glycine
Supplier: Cayman Chemical
Supplier-Nr: 9000326


Application: Bioactive lipid assays
MW: 337.5 D
Formula: C20H35NO3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2764-03-6| Find alternatives

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