Linoleic Acid-d4

Linoleic acid-d4 is intended for use as an internal standard for the quantification of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by GC- or LC-MS. Linoleic acid is an essential omega-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 µM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.Formal Name: 9Z,12Z-octadecadienoic-9,10,12,13-d4 acid. CAS Number: 79050-23-0. Synonyms: C18:2(9Z,12Z)-d4, C18:2 n-6-d4, FA 18:2-d4, 9,12-Octadecadienoic Acid-d4, Telfairic Acid-d4. Molecular Formula: C18H28D4O2. Formula Weight: 284.5. Purity: >99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid), DMF: >100 mg/ml (from Oleic Acid), DMSO: >100 mg/ml (from Oleic Acid), Ethanol: >100 mg/ml (from Oleic Acid), PBS pH 7.2: <100 µg/ml (from Oleic Acid). SMILES: CCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCCCCC(O)=O. InChi Code: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-/i6D,7D,9D,10D. InChi Key: OYHQOLUKZRVURQ-GPTDOFLBSA-N. Side Chain Carbon Sum: 18:2.