Hydrocortisone

Hydrocortisone
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay20739-1 1 g -

6 - 10 business days*

38.00€
Cay20739-5 5 g -

6 - 10 business days*

123.00€
Cay20739-10 10 g -

6 - 10 business days*

225.00€
Cay20739-25 25 g -

6 - 10 business days*

472.00€
 
Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the... more
Product information "Hydrocortisone"
Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson's disease.Formal Name: (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione. CAS Number: 50-23-7. Synonyms: Cortisol, Dihydrocostisone, NSC 10483. Molecular Formula: C21H30O5. Formula Weight: 362.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/mL, DMF:PBS (pH 7.2) (1:4): 0.20 mg/mL, DMSO: 20 mg/mL, Ethanol: 2 mg/mL. lambdamax: 242 nm. SMILES: [H][C@]12[C@@]([C@@](CC[C@]3(O)C(CO)=O)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(CC[C@@]41C)=O. InChi Code: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1. InChi Key: JYGXADMDTFJGBT-VWUMJDOOSA-N.
Keywords: Cortisol, Dihydrocostisone, NSC 10483, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione
Supplier: Cayman Chemical
Supplier-Nr: 20739

Properties

Application: Natural glucocorticoid
MW: 362.5 D
Formula: C21H30O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 50-23-7| Matching products
KEGG ID : K05771 | Matching products

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H361
P Phrases: P201, P202, P280, P308+313, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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