HEPC

Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity. HEPC is a truncated analog of phosphatidylcholine with the entire sn-1 substituent deleted, and with a hexadecylthioester in the sn-2 position. HEPC is a substrate for Type II phospholipase A2 (PLA2) enzymes, such as porcine pancreatic, bee venom, and snake venom PLA2. The intrinsic biological activity of HEPC has not been actively investigated.Formal Name: 4-oxide-4-hydroxy-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-thia-4-phosphatetracosan-1-aminium, inner salt. CAS Number: 60793-01-3. Synonyms: 2-Hexadecanoylthio-1-Ethylphosphorylcholine. Molecular Formula: C23H48NO5PS. Formula Weight: 481.7. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: CCCCCCCCCCCCCCCC(SCCOP([O-])(OCC[N+](C)(C)C)=O)=O. InChi Code: InChI=1S/C23H48NO5PS/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(25)31-22-21-29-30(26,27)28-20-19-24(2,3)4/h5-22H2,1-4H3. InChi Key: BDPQVGIMLZYZQA-UHFFFAOYSA-N.