Eicosapentaenoyl Ethanolamide

Eicosapentaenoyl ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes. Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA also has anti-inflammatory properties, suppressing the expression of IL-6 and MCP-1 in 3T3-L1 adipocytes in response to lipopolysaccharide.Formal Name: N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide. CAS Number: 109001-03-8. Synonyms: EPEA. Molecular Formula: C22H35NO2. Formula Weight: 345.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. SMILES: O=C(NCCO)CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC. InChi Code: InChI=1S/C22H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h3-4,6-7,9-10,12-13,15-16,24H,2,5,8,11,14,17-21H2,1H3,(H,23,25)/b4-3-,7-6-,10-9-,13-12-,16-15-. InChi Key: OVKKNJPJQKTXIT-JLNKQSITSA-N.