Decylubiquinone

Decylubiquinone is an analog of ubiquinone (coenzyme Q10, Cay-11506). It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. Decylubiquinone inhibited opening of the mitochondrial permeability transition pore in response to calcium overload in rat liver mitochondria in different cell lines at concentrations between 50-100 µM.Formal Name: 2-decyl-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione. CAS Number: 55486-00-5. Molecular Formula: C19H30O4. Formula Weight: 322.4. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 15 mg/ml, Ethanol:PBS (pH 7.2) (1:3): 0.3 mg/ml. lambdamax: 277, 403 nm. SMILES: COC(C(C(CCCCCCCCCC)=C1C)=O)=C(OC)C1=O. InChi Code: InChI=1S/C19H30O4/c1-5-6-7-8-9-10-11-12-13-15-14(2)16(20)18(22-3)19(23-4)17(15)21/h5-13H2,1-4H3. InChi Key: VMEGFMNVSYVVOM-UHFFFAOYSA-N.