D-myo-Inositol-1,4,5-triphosphate (potassium salt)

D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.Formal Name: D-myo-inositol-1,2,5-tris(dihydrogen phosphate), tripotassium salt. CAS Number: 141611-11-2. Synonyms: Ins(1,4,5)-P3 (potassium salt), 1,4,5-IP3 (potassium salt). Molecular Formula: C6H12O15P3 . 3K. Formula Weight: 534.4. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. Solubility: PBS pH 7.2: >50 mg/ml. SMILES: O[C@H]1[C@@H](OP([O-])(O)=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@H]1O.[K+].[K+].[K+]. InChi Code: InChI=1S/C6H15O15P3.3K/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12,,,/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18),,,/q,3*+1/p-3/t1-,2+,3+,4?,5?,6?,,,/m1.../s1. InChi Key: MQMSEISCCNPXIL-FMCZHWOXSA-K.