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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor... more
Product information "(+)-Cloprostenol methyl amide"
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2alpha in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2alpha. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2alpha in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2alpha. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol methyl amide is a more lipid soluble form of (+)-cloprostenol. Amides of PGs may serve as prodrugs, under the condition they are hydrolyzed appropriately in certain tissues to generate the bioactive free acid.Formal Name: (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl amide. Synonyms: D-Cloprostenol methyl amide, (+)-16-m-Chlorophenoxy tetranor PGF2alpha methyl amide. Molecular Formula: C23H32ClNO5. Formula Weight: 438.0. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(NC)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(Cl)=C2)[C@H](O)C1. InChi Code: InChI=1S/C23H32ClNO5/c1-25-23(29)10-5-3-2-4-9-19-20(22(28)14-21(19)27)12-11-17(26)15-30-18-8-6-7-16(24)13-18/h2,4,6-8,11-13,17,19-22,26-28H,3,5,9-10,14-15H2,1H3,(H,25,29)/b4-2-,12-11+/t17-,19-,20-,21+,22-/m1/s1. InChi Key: IFOQFZVPFCRSLM-OWEKAKITSA-N.
Keywords: | (+)-16-m-Chlorophenoxy tetranor PGF2alpha methyl amide, D-Cloprostenol methyl amide, (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, methyl amide |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10010495 |
Properties
Application: | FP receptor agonist, luteolytic agent |
MW: | 438 D |
Formula: | C23H32ClNO5 |
Purity: | >98% |
Format: | Solution |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H225, H319, H360 |
P Phrases: | P201, P202, P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P308+313, P337+313, P370+378, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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