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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay18210-100 | 100 µg | - |
6 - 10 business days* |
125.00€
|
|||
Cay18210-500 | 500 µg | - |
6 - 10 business days* |
205.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Carbaprostacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex... more
Product information "Carbaprostacyclin"
Carbaprostacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. This implies rapid metabolic inactivation of carbaprostacyclin. Carbaprostacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of carbaprostacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 µM.Formal Name: 6,9alpha-methylene-11alpha,15S-dihydroxy-prosta-5E,13E-dien-1-oic acid. CAS Number: 69552-46-1. Synonyms: Carbacyclin, cPGI. Molecular Formula: C21H34O4. Formula Weight: 350.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >10 mg/ml (from 6B-PGI2), DMSO: >5 mg/ml (from 6B-PGI2), Ethanol: >20 mg/ml (from 6B-PGI2), PBS pH 7.2: >80 µg/ml (from 6B-PGI2). SMILES: O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C/C(C2)=C/CCCC(O)=O)[C@@H]2C1. InChi Code: InChI=1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7+/t16-,17-,18+,19-,20+/m0/s1. InChi Key: XZFRIPGNUQRGPI-WBQKLGIQSA-N.
Keywords: | Carbacyclin, cPGI, 6,9alpha-methylene-11alpha,15S-dihydroxy-prosta-5E,13E-dien-1-oic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 18210 |
Properties
Application: | PGI2 analog |
MW: | 350.5 D |
Formula: | C21H34O4 |
Purity: | >98% |
Format: | Solution |
Database Information
CAS : | 69552-46-1| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H225, H302, H312, H332, H336 |
P Phrases: | P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+310, P302+352, P303+361+353, P304+340, P312, P321, P330, P361+364, P370+378, P403+233, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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