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Arachidonoyl ethanolamide (AEA, Cay-90050), also known as anandamide, is an endogenous ligand of the cannabinoid receptors. AEA is metabolized by fatty acid amide hydrolase (FAAH) to give arachidonic acid (Cay-90010) and ethanolamine. ARN1203 is a fluorinated analog of AEA that serves as a substrate of FAAH (Km = 29 µM). Fluorinated substrates, like ARN1023, are used in 'n-fluorine atoms for biochemical screening' (n-FABS) assays, NMR functional assays that directly measure the conversion of the substrate into product. ARN1203 is used to perform n-FABS against FAAH to identify novel inhibitors.{25931, 25932,25933}Formal Name: N-(3-fluoro-2-hydroxypropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide. CAS Number: 1428445-15-1. Molecular Formula: C23H38FNO2. Formula Weight: 379.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. SMILES: O=C(NCC(O)CF)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC. InChi Code: InChI=1S/C23H38FNO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(27)25-21-22(26)20-24/h6-7,9-10,12-13,15-16,22,26H,2-5,8,11,14,17-21H2,1H3,(H,25,27)/b7-6-,10-9-,13-12-,16-15-. InChi Key: IXPSZMYVPAPSRW-DOFZRALJSA-N.
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