Arachidonoyl Glycine

Arachidonoyl glycine (N-arachidonyl glycine, NAGly) has been isolated from cell cultures treated with arachidonoyl ethanolamide (AEA, anandamide), from extracts of mammalian brain, and has also been synthesized as an analog of AEA for structure/activity testing. NAGly may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. NAGly is reported to have analgesic activities in whole animal experiments. Since it seems to be a very poor ligand for the CB1 receptor, these effects are probably mediated via other signaling pathways.Formal Name: N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine. CAS Number: 179113-91-8. Synonyms: N-Arachidonyl Glycine, NAGly. Molecular Formula: C22H35NO3. Formula Weight: 361.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 20 mg/ml, DMSO: 15 mg/ml, Ethanol: 50 mg/ml, Methyl Acetate: 10 mg/ml, PBS (pH 7.2): 2 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC. InChi Code: InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21(24)23-20-22(25)26/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-15-. InChi Key: YLEARPUNMCCKMP-DOFZRALJSA-N.