No results were found for the filter!
(25S)-Delta7-Dafachronic Acid
Item number: Cay14101-100
During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
| Keywords: | UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid |
| Application: | DAF-12 inhibitor |
| CAS | 949004-12-0 |
| MW: | 414.6 D |
From 429.00€
*
5-OxoETE
Item number: Cay34250-25
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway...
| Keywords: | 5-KETE, 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Polyunsaturated keto acid, neutrophil migration stimulator |
| CAS | 106154-18-1 |
| MW: | 318.5 D |
From 116.00€
*
10(S)-hydroxy Stearic Acid
Item number: Cay44258-1
10(S)-hydroxy Stearic acid is a hydroxy fatty acid and minor metabolite of oleic acid (Cay90260, Cay24659) formed by gut microbiota and other bacteria. It inhibits the proliferation of A549 lung cancer and Caco-2 colon cancer cells when used at concentrations of 50 and 100 µM. SMILES CCCCCCCC[C@H](O)CCCCCCCCC(O)=O...
| Keywords: | 10(S)-HODA, 10(S)-HSA, 10(S)-hydroxy ODA, 10(S)-Hydroxyoctadecanoic Acid, FA 18:0,O, (S)-10-hydroxy-octadecanoic acid |
| Application: | Hydroxy fatty acid |
| CAS | 67042-09-5 |
| MW: | 300.48 D |
From 147.00€
*
4-hydroxy Hexenal
Item number: Cay32060-1
4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized omega-3 fatty acids such as DHA.Formal Name: (±)-4-hydroxy-2E-hexenal. CAS Number: 17427-21-3. Synonyms: 4-HHE. Molecular Formula: C6H10O2. Formula Weight: 114.1. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol....
| Keywords: | 4-HHE, (±)-4-hydroxy-2E-hexenal |
| Application: | Lipid peroxidation studies |
| CAS | 17427-21-3 |
| MW: | 114.1 D |
From 112.00€
*
(±)7-HDHA
Item number: Cay33300-25
(±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells and human neutrophils also produces 7-HDHA. However, the enzymatic product is most likely the...
| Keywords: | (±)7-HDoHE, 7-hydroxy Docosahexaenoic Acid, (±)7-hydroxy-4Z,8E,10Z,13Z,16Z,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-55-5 |
| MW: | 344.5 D |
From 115.00€
*
12-OxoETE
Item number: Cay34580-25
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a...
| Keywords: | 12-KETE, 12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 108437-64-5 |
| MW: | 318.5 D |
From 196.00€
*
8(S),15(S)-DiHETE
Item number: Cay35370-25
8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 µM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.Formal...
| Keywords: | 8S,15S-dihydroxy-5Z,9E,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 80234-65-7 |
| MW: | 336.5 D |
From 142.00€
*
(R)-Bromoenol lactone
Item number: Cay10006800-1
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli....
| Keywords: | (R)-BEL, 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl)-2H-pyran-2-one |
| Application: | iPLA2gamma inhibitor |
| CAS | 478288-90-3 |
| MW: | 317.2 D |
From 49.00€
*
Prostaglandin A1
Item number: Cay10010-50
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
| Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 14152-28-4 |
| MW: | 336.5 D |
From 68.00€
*
5-OxoETE-d7
Item number: Cay334250-25
5-OxoETE-d7 contains seven deuterium atoms at the 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5-oxoETE by GC- or LC-mass spectrometry. 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates...
| Keywords: | 5-KETE-d7, 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic-6,8,9,11,12,14,15-d7 acid |
| Application: | Standard |
| CAS | 1881277-29-7 |
| MW: | 325.5 D |
From 309.00€
*
(±)16-HDHA
Item number: Cay33600-25
(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.Formal Name:...
| Keywords: | (±)16-HDoHE, 16-hydroxy Docosahexaenoic Acid, (±)16-hydroxy-4Z,7Z,10Z,13Z,17E,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-51-1 |
| MW: | 344.5 D |
From 115.00€
*
(±)11-HETE
Item number: Cay34500-25
(±)11-HETE is an oxylipin formed non-enzymatically from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). Levels of (±)11-HETE are increased in an in vitro model of lipid peroxidation induced by ferrous ammonium sulfate (FAS) in rat brain homogenates. Levels are also increased in rat liver in an in vivo model...
| Keywords: | (±)11-Hydroxyeicosatetraenoic Acid, (±)11-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 73804-65-6 |
| MW: | 320.5 D |
From 139.00€
*