No results were found for the filter!
SIL Lipid
Item number: Cay40801-1
SIL lipid is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro. LNPs containing SIL lipid and encapsulating siRNA targeting mRNA encoding the purinergic P2X7 receptor decrease protein levels of the purinergic P2X7 receptor, reduce...
| Keywords: | N,N',N''-(nitrilotri-2,1-ethanediyl)tris[N-methyl-beta-alanine, 1,1',1''-tridodecyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 1566559-79-2 |
| MW: | 909.5 D |
From 57.00€
*
C14-O2
Item number: Cay40805-1
C14-O2 is an ionizable cationic lipid (apparent pKa = 6.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing C14-O2 and encapsulating mRNA encoding chimeric antigen receptor (CAR) induce CAR expression and B cell aplasia in mice.CAS...
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2639634-77-6 |
| MW: | 1453.4 D |
From 157.00€
*
U-46619 serinol amide
Item number: Cay40870-1
U-46619 serinol amide is a derivative of the TP receptor agonist U-46619 (Cay-16450).Formal Name: (Z)-N-(1,3-dihydroxypropan-2-yl)-7-((1R,4S,5S,6R)-6-((S,E)-3-hydroxyoct-1-en-1-yl)-2-oxabicyclo[2.2.1]heptan-5-yl)hept-5-enamide. Synonyms: 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha serinol amide,...
| Keywords: | 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha serinol amide, 9,11-dideoxy-9alpha,11alpha-methanoepoxy Prostaglandin... |
| Application: | U-46619 derivative |
| MW: | 423.6 D |
From 112.00€
*
Aspinolide B
Item number: Cay40873-500
Aspinolide B is a polyketide synthase-derived aspinolide that has been found in T. arundinaceum and has plant growth regulatory activity. It promotes the growth of S. lycopersicum lateral roots when used at a concentration of 50 µg/ml.Formal Name: (2E)-2-butenoic acid,...
| Keywords: | (2E)-2-butenoic acid, (2R,3S,4E,6R,7S)-3,6,7,8,9,10-hexahydro-6,7-dihydroxy-2-methyl-10-oxo-2H-oxecin-3-yl ester |
| Application: | Aspinolide, plant growth regulatory agent |
| CAS | 188605-15-4 |
| MW: | 284.3 D |
88.00€
*
IZ-Chol
Item number: Cay40963-10
IZ-Chol is an ionizable cationic lipid (pKas = 7.29 and 3.96) containing cholesterol (Cay-9003100, Cay-39088). LNPs containing IZ-chol can be complexed with DNA, with the plasmid-binding efficacy dependent, in part, on the type of helper lipids in the LNP formulation.Formal Name:...
| Keywords: | IZ-Cholesterol, [3-(1H-imidazol-1-yl)propyl]carbamate, cholest-5-en-3beta-ol |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 191990-35-9 |
| MW: | 537.8 D |
From 147.00€
*
5R(6S)-EET
Item number: Cay9004343-100
5R(6S)-EET is an oxylipin. It depolarizes transepithelial voltage in isolated rabbit renal cortical collecting duct when applied to the luminal side at a concentration of 1 µM to a lesser extent than 5S(6R)-EET (Cay-9004349). In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-delta-lactone, which can be...
| Keywords: | 5R(6S)-EpETrE, 5R(6S)-epoxy-8(Z),11(Z),14(Z)-ETrE, 5R(6S)-epoxy-all-cis-8,11,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin |
| CAS | 98103-46-9 |
| MW: | 320.5 D |
From 426.00€
*
11R(12S)-EET
Item number: Cay9004344-100
11R(12S)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is selectively formed from arachidonic acid by the cytochrome P450 (CYP) isoform CYP2C23 and CYP2C24 over CYP2B2, as well as CYP2C8 over CYP2C9. 11R(12S)-EET (50 nM) activates large-conductance...
| Keywords: | 11R(12S)-EpETrE, 11R(12S)-Epoxy-5(Z),8(Z),14(Z)-ETrE, 11R(12S)-Epoxy-all-cis-5,8,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 123931-38-4 |
| MW: | 320.5 D |
From 444.00€
*
8S(9R)-EET
Item number: Cay9004345-100
8S(9R)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by the cytochrome P450 (CYP) isoforms CYP1A1, CYP1A2, CYP2B1, and CYP2B2. 8S(9R)-EET induces relaxation of precontracted isolated dog epicardial arterioles (EC50 = 121...
| Keywords: | 8S(9R)-EpETrE, 8S(9R)-epoxy-5(Z),11(Z),14(Z)-ETrE, 8S(9R)-epoxy-all-cis-5,11,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 123931-39-5 |
| MW: | 320.5 D |
From 426.00€
*
8R(9S)-EET
Item number: Cay9004347-100
8R(9S)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by the cytochrome P450 (CYP) isoform CYP2C11. 8R(9S)-EET induces relaxation of precontracted isolated dog epicardial arterioles (EC50 = 15 pM).Formal Name:...
| Keywords: | 8R(9S)-EpETrE, 8R(9S)-epoxy-5(Z),11(Z),14(Z)-ETrE, 8R(9S)-epoxy-all-cis-5,11,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 129172-62-9 |
| MW: | 320.5 D |
From 426.00€
*
11S(12R)-EET
Item number: Cay9004348-100
11S(12R)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is selectively formed from arachidonic acid by the cytochrome P450 (CYP) isoform CYP2B2 over CYP2C23 and CYP2C24, as well as CYP2C9 over CYP2C8. 11S(12R)-EET (50 nM) activates large-conductance...
| Keywords: | 11S(12R)-EpETrE, 11S(12R)-epoxy-5(Z),8(Z),14(Z)-ETrE, 11S(12R)-epoxy-all-cis-5,8,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 123931-40-8 |
| MW: | 320.5 D |
From 103.00€
*
5S(6R)-EET
Item number: Cay9004349-100
5S(6R)-EET is an oxylipin. It depolarizes transepithelial voltage in isolated rabbit renal cortical collecting duct when applied to the luminal side at a concentration of 1 µM. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-delta-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.Formal...
| Keywords: | 5S(6R)-EpETrE, 5S(6R)-epoxy-8(Z),11(Z),14(Z)-ETrE, 5S(6R)-epoxy-all-cis-8,11,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin |
| CAS | 98103-47-0 |
| MW: | 320.5 D |
From 426.00€
*
14R(15S)-EET
Item number: Cay9004351-100
14R(15S)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. 14R(15S)-EET (10 µM) induces relaxation of precontracted isolated bovine coronary arteries.Formal Name:...
| Keywords: | 14R(15S)-EpETrE, 14R(15S)-epoxy-5(Z),8(Z),11(Z)-ETrE, 14R(15S)-epoxy-all-cis-5,8,11-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 98103-48-1 |
| MW: | 320.5 D |
From 426.00€
*