8R(9S)-EET

8R(9S)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by the cytochrome P450 (CYP) isoform CYP2C11. 8R(9S)-EET induces relaxation of precontracted isolated dog epicardial arterioles (EC50 = 15 pM).Formal Name: (5Z)-7-[(2R,3S)-3-(2Z,5Z)-2,5-undecadien-1-yl-2-oxiranyl]-5-heptenoic acid. CAS Number: 129172-62-9. Synonyms: 8R(9S)-epoxy-all-cis-5,11,14-Eicosatrienoic Acid, 8R(9S)-EpETrE, 8R(9S)-Epoxyeicosatrienoic Acid, 8R(9S)-epoxy-5(Z),11(Z),14(Z)-ETrE, FA 20:4,O. Molecular Formula: C20H32O3. Formula Weight: 320.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Acetonitrile: Sparingly Soluble: 1-10 mg/ml, Ethanol: Slightly Soluble: 0.1-1 mg/ml. SMILES: CCCCC/C=C\C/C=C\C[C@H](O1)[C@H]1C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-12-15-18-19(23-18)16-13-10-11-14-17-20(21)22/h6-7,9-10,12-13,18-19H,2-5,8,11,14-17H2,1H3,(H,21,22)/b7-6-,12-9-,13-10-/t18-,19+/m0/s1. InChi Key: DBWQSCSXHFNTMO-QJVNBQAESA-N.