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1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC
Item number: Cay40522-1
1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC is a lysophospholipid. It increases cAMP production in human pancreatic beta cells, an effect that can be blocked by the GPR55 antagonist CID-16020046 (Cay-15247) or the GPR119 antagonist C8. 1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC increases glucose-stimulated insulin...
| Keywords: | 16:1 Lyso PC, 1-Hexadecenoyl-2-hydroxy-sn-glycero-3-PC, LPC(16:1), PC(16:1/0:0),... |
| Application: | Lysophospholipid |
| CAS | 76790-27-7 |
| MW: | 493.6 D |
From 49.00€
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13-OxoODE Alkyne
Item number: Cay9004372-100
13-OxoODE Alkyne is a clickable form of the oxylipin 13-oxoODE (Cay-38620) containing an omega-terminal alkyne.Formal Name: 13-oxooctadeca-9Z,11E-dien-17-ynoic acid. Synonyms: ClickTag(TM) 13-OxoODE Alkyne, FA 18:3,O Alkyne, 13-KODE Alkyne, 13-keto-9(Z),11(E)-Octadecadienoic Acid Alkyne, 13-keto-9(Z),11(E)-ODE...
| Keywords: | 13-keto-9(Z),11(E)-Octadecadienoic Acid Alkyne, 13-keto-9(Z),11(E)-ODE Alkyne, 13-KODE Alkyne,... |
| Application: | 13-oxoODE, clickable form |
| MW: | 290.4 D |
From 139.00€
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BPR0912
Item number: Cay10678-1
BPR0912 is a cannabinoid 1 (CB1) receptor inverse agonist (IC50 = 8.5 nM for the human receptor). It is selective for CB1 over CB2 receptors (IC50 = 604.9 nM for the human receptor). In vivo, BPR0912 (10 mg/kg per day) inhibits diet-induced increases in body weight, epididymal and inguinal fat pad mass, and serum...
| Keywords: | TM38837,... |
| Application: | CB1 receptor inverse agonist |
| CAS | 1253641-65-4 |
| MW: | 617.5 D |
From 38.00€
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1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE
Item number: Cay25589-25
1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a form of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE, Cay-15092) that contains two methyl groups on the sn-3 moiety. In aqueous suspensions, it lowers the phase transition temperature compared with aqueous suspensions of 1,2-DPPE and...
| Keywords: | 1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-Phosphoethanolamine, 1,2-N,NMe2DPPE, 16:0 Dimethyl PE, hexadecanoic acid,... |
| Application: | Liposomes & monolayer formation |
| CAS | 3922-61-0 |
| MW: | 720 D |
From 127.00€
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Ganglioside GM1 (bovine) (ammonium salt)
Item number: Cay31548-1
Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane. It associates with growth factor receptors, including TrkA,...
| Keywords: | GM1, Monosialoganglioside GM1,... |
| Application: | Monosialylated gangliosides |
| CAS | 1007119-81-4 |
| MW: | 1563.9 D |
177.00€
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DSPE-PEG(2000) Cyanur
Item number: Cay37797-1
DSPE-PEG(2000) Cyanur is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE, Cay-15095) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of micro RNA (miRNA) in vitro. LNPs containing DSPE-PEG(2000) cyanur, encapsulating let-7a miRNA, and conjugated to the Eph tyrosine kinase...
| Keywords: | 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000 Cyanur,... |
| Application: | PEGylated DSPE, LNP formation |
| CAS | 1246304-74-4 |
| MW: | 1044.2 D |
From 38.00€
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A17
Item number: Cay39686-100
A17 is a bile acid derivative. It reduces triglyceride accumulation induced by oleic acid (Cay-90260, Cay-24659), increases cell viability, and decreases oleic acid-induced lipid peroxidation in primary rat hepatocytes when used at concentrations of 10 and 25 µM. A17 (25 µM) reduces levels of CD36, also known as...
| Keywords: | (3alpha,5beta,7beta)-3,7-bis(formyloxy)-N-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-cholan-24-amide |
| Application: | Bile acid derivative |
| CAS | 2568186-47-8 |
| MW: | 533.7 D |
From 146.00€
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E12CA1A3
Item number: Cay40415-1
E12CA1A3 is an ionizable cationic lipid (pKa = 6.4) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing E12CA1A3 and encapsulating an mRNA reporter induce luciferase reporter expression in mouse bone marrow-derived dendritic cells (BMDCs)...
| Keywords: | 2-hexyl-decanoic acid, 2-[4-(dimethylamino)-1-oxobutoxy]dodecyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2778182-26-4 |
| MW: | 553.9 D |
From 53.00€
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(3beta,4beta,17beta)-17-(2-Pyridinylmethyl)androst-5-ene-...
Item number: Cay40438-1
(3beta,4beta,17beta)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol is a sterol lipid and derivative of 5-androstenetriol (Cay-35273). It is cytotoxic to MDA-MB-231 breast, PC3 prostate, HeLa cervical, and HT-29 colon cancer cells (IC50s = 9, 52.1, 26.6, and 8 µM, respectively) but not MRC-5 fibroblasts (IC50 =...
| Keywords: | 17-(2-pyridinylmethyl)-androst-5-ene-3beta,4beta,17beta-triol |
| Application: | Sterol lipid, 5-androstenetriol derivative |
| CAS | 1393651-00-7 |
| MW: | 397.6 D |
From 49.00€
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C6 Biotin Ganglioside GT1b (d18:1/6:0) (ammonium salt)
Item number: Cay40501-1
C6 Biotin Ganglioside GT1b (d18:1/6:0) is an affinity probe that allows ganglioside GT1b (Cay-31712, Cay-31592, Cay-19579) to be detected or immobilized through interaction with the biotin ligand. As this product is derived from a natural source, there may be variations in the sphingoid backbone.Synonyms:...
| Keywords: | Biotin-C6:0-GT1b, N-hexanoyl-Biotin-Ganglioside G1, N-hexanoyl-Biotin-Trisialoganglioside GT1b |
| Application: | Ganglioside GT1b binding partner affinity probe |
| MW: | 2253.4 D |
From 1,036.00€
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80-O18
Item number: Cay40611-10
80-O18 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for use in vitro. An LNP complex containing 80-O18 and a Cre-GFP fusion protein tagged with one of three assay-specific chloroalkane tags displays high total cellular uptake and functional delivery in reporter...
| Keywords: | N-[3-(dimethylamino)propyl]-N-[3-(octadecyloxy)-3-oxopropyl]-beta-alanine, octadecyl ester |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 1638334-27-6 |
| MW: | 751.3 D |
From 139.00€
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9CCN
Item number: Cay40739-1
9CCN is a cholesterol ester and oxidized anionic lipid. It has been found both intracellularly in plaque macrophages and extracellularly in atherosclerotic lesions where it acts as an 'eat-me' signal to facilitate phagocytic uptake of apoptotic debris. 9CCN has been used in the formation of lipid nanoparticles...
| Keywords: | Cholesteryl-9-carboxynonanoate, (3beta)-cholest-5-en-3-ol, 3-(hydrogen nonanedioate) |
| Application: | Cholesterol ester, oxidized anionic lipid, LNP formation |
| CAS | 596592-83-5 |
| MW: | 556.9 D |
From 93.00€
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