8-iso-15-keto Prostaglandin F2beta

8-iso-15-keto Prostaglandin F2beta
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008539-100 100 µg -

6 - 10 business days*

Cay10008539-500 500 µg -

6 - 10 business days*

Cay10008539-1 1 mg -

6 - 10 business days*

8-iso Prostaglandin F2beta (8-iso PGF2beta) is an isomer of PGF2alpha of non-enzymatic origin. It... more
Product information "8-iso-15-keto Prostaglandin F2beta"
8-iso Prostaglandin F2beta (8-iso PGF2beta) is an isomer of PGF2alpha of non-enzymatic origin. It is one of 64 possible isomers of PGF2alpha which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2beta exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2beta moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF2alpha. 8-iso-15-keto PGF2beta is a potential metabolite of 8-iso PGF2beta via the 15-hydroxy PG dehydrogenase pathway. There are no published reports on the formation or biological activity of 8-iso-15-keto PGF2beta. Formal Name: 9beta,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid. CAS Number: 1621482-36-7. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 234 nm. SMILES: O[C@@H]1C[C@@H](O)[C@@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/C(CCCCC)=O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-19,22-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17+,18+,19+/m0/s1. InChi Key: LOLJEILMPWPILA-WZDCOHRSSA-N.
Keywords: 9beta,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10008539


Application: Bioactive lipid assays
MW: 352.5 D
Formula: C20H32O5
Purity: >95%
Format: Solution

Database Information

CAS : 1621482-36-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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