(±)8-HDHA

(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.Formal Name: (±)8-hydroxy-4Z,6E,10Z,13Z,16Z,19Z-docosahexaenoic acid. CAS Number: 90780-54-4. Synonyms: 8-hydroxy Docosahexaenoic Acid, (±)8-HDoHE. Molecular Formula: C22H32O3. Formula Weight: 344.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS (pH 7.2): 0.8 mg/ml. lambdamax: 234 nm. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\CC(O)\C=C\C=C\CCC(=O)O. InChi Code: InChI=1S/C22H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-15-18-21(23)19-16-13-14-17-20-22(24)25/h3-4,6-7,9-10,12-16,19,21,23H,2,5,8,11,17-18,20H2,1H3,(H,24,25)/b4-3-,7-6-,10-9-,14-13-,15-12-,19-16+. InChi Key: ZHBVYDMSPDDAKE-VTIZNUJUSA-N.