4-Allylcatechol

4-Allylcatechol is a phenol that has been found in P. betle and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals, reduces the formation of thiobarbituric acid reactive substances (TBARS), and inhibits xanthine oxidase in cell-free assays (IC50s = 20.17, 2, and 16.7 µM, respectively). 4-Allylcatechol is cytotoxic to HT-29 colon cancer cells (IC50 = 30 µg/ml). It reduces paw edema and arthritic paw tissue homogenate levels of IL-1beta, prostaglandin E2 (PGE2, Cay-14010), leukotriene B4 (LTB4, Cay-20110), and nitric oxide (NO) in a mouse model of steam-killed M. tuberculosis-induced arthritis when administered at a dose of 4 mg/kg. 4-Allylcatechol has been used as a precursor in the synthesis of, and is a metabolite of, safrole.Formal Name: 4-(2-propen-1-yl)-1,2-benzenediol. CAS Number: 1126-61-0. Synonyms: Hydroxychavicol, 4-Allylbenzene-1,2-diol, 4-Allylpyrocatechol, 1,2-Dihydroxy-4-allylbenzene. Molecular Formula: C9H10O2. Formula Weight: 150.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: OC1=CC=C(CC=C)C=C1O. InChi Code: InChI=1S/C9H10O2/c1-2-3-7-4-5-8(10)9(11)6-7/h2,4-6,10-11H,1,3H2. InChi Key: FHEHIXJLCWUPCZ-UHFFFAOYSA-N. Origin: Synthetic.